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Advancements in molecular biology technology allowed the development of promising biomarkers, such as Peripheral blood gene expression profiling (GEP) and cell-free DNA (cfDNA), for minimally invasive characterisation of allograft rejection.

The use of circulating GEP and cfDNA may offer advantages over invasive tissue biopsy as a quantitative measure for detection of transplant rejection and immunosuppression optimisation. However, there is no standard recognition of the usage of this new technology.

The objectives of this project are – 

  • To provide knowledge and information to the transplantation community, including patients, advocates and healthcare professionals
  • Discuss and disseminate new and innovative diagnosis and monitoring practices and promote their use throughout the wider healthcare community
  • Equip all relevant community health care professionals and advocates with the relevant tools and skills to place patients onto the most appropriate care pathways

ESOT, with the kind support from CareDx, Eurofins, and Natera will lead projects to foster awareness and education in the field of Molecular Biology Testing for Non-Invasive Diagnosis of Allograft Rejection.

Working Groups


John Friedewald
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Dany Anglicheau
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Oriol Bestard
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Heart & Lung

Luciano Potena
ESOT Past President 2023-2025
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Sean Agbor-Enoh
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Ingvild Birschmann
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Marisa Crespo Leiro
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Kiran Khush
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Javier Segovia
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Robin Vos
ECTTA Chair 2021-2023
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Marina Berenguer
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Eleonora De Martin
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Amelia Hessheimer
Courses and masterclasses lead 2022-2025
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Josh Levitsky
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Valeria Mas
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This project is possible thanks to the kind support of

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