WEBINAR: Challenges and scientific advancements in biomarkers paediatric Transplantation

The webinar “Challenges and scientific advancements in biomarkers in paediatric transplantation” of the relaunched ESOT Basic Science Committee webinar series aims to build links between ESOT and IPTA. As such, we invite professionals with clinical and scientific expertise in paediatric kidney transplantation to present and discuss the unique challenges of translational research in this vulnerable cohort. Biomarkers for the early detection of rejection in kidney transplant recipients are urgently needed. They promise timely and refined diagnosis to facilitate early treatment, and especially in pediatric patients to reduce diagnostic burden from repeated biopsies. However, unique challenges lay in the extrapolation, translation, analytical, and clinical study and application in pediatric transplant recipients. In partnership with IPTA we aim to address and discuss these unique challenges and opportunities in pediatric transplantation. If well received, we plan to build on this partnership to add future conjoint webinars to the ESOT Basic Science Committee webinar series.

Need:
Biomarkers for the early detection of rejection in kidney transplant recipients are urgently needed to provide timely treatment. Studies in adult and pediatric recipients are emerging, exemplified by the biomarker donor-derived cell-free DNA. However, pediatric specifics and unique challenges to biomarker research in this population are seldom discussed or addressed. These unique challenges and opportunities will be discussed during this webinar coming from the results of the largest cross-sectional donor-derived cell-free DNA study in adult and pediatric recipients and finally addressing diagnostic performance of donor-derived cell-free DNA for (pediatric) research and clinical application.

Educational objectives:
Stimulating thought, generating scientific discourse, building links between ESOT and IPTA.

Programme:

• Introduction – Fabian Eibensteiner
• Donor-derived cell-free DNA to detect kidney allograft rejection across all ages – Olivier Aubert
• Diagnostic performance of dd-cfDNA – Michael Oellerich
• Q&A – Evgenia Preka (IPTA)

Please fill up the Webinar Registration to get an email for your direct access link.