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ESOT Masterclass

Primary Topics:
Biomarkers
Start Date:
Friday, June 14th 2024
End Date:
Saturday, June 15th 2024
Timezone:
CEST
Country:
Krakow, Poland
Description & Objectives:

Advancements in molecular biology technology allowed the development of promising biomarkers, such as Peripheral blood gene expression profiling (GEP) and cell-free DNA (cfDNA), for minimally invasive diagnosis and characterisation of allograft rejection.
The use of circulating GEP and cfDNA may offer advantages over invasive tissue biopsy as a quantitative measure for detection of transplant rejection, immunosuppression optimisation and follow-up after treatment. However, there is no standard recognition of the usage of this new technology.

With the intention of fostering awareness around this topic, during the TLJ 3.0 Consensus conference held in Prague, November 2022, a panel of experts developed guidelines on the use of Molecular Biology testing for Non-Invasive Diagnosis of Allograft Rejection pertaining to the Kidney, Heart & Lung, and Liver. These guidelines were submitted in the form of three papers and have been published on Transplant International.

This masterclass was designed based on the outcomes of these guidelines. It will cover all the cutting-edge technologies that are about to revolutionise the transplantation field, including cell-free DNA, new plasma, urinary and immune function biomarkers, gene-expression profiling, as well as recent advances on HLA and non-HLA antibodies.

Learning Objectives:

After attending this masterclass participants will be able to:

  • Gain insight into all the cutting-edge technologies in the transplantation field;
  • Learning the ESOT recommendations on testing for non-invasive diagnosis of SOT rejection
  • Put recent discoveries into clinical context.https://esot.org/wp-content/uploads/2024/04/ESOT_Masterclass_ScientificProgramme_vv10-May_c.pd

Download the programme at this link

Target Group:

Solid Organ Transplant professionals who are within 5 years of senior appointment. 

Professional Background: Nephrology, Cardio Thoracic, Scientist, Allied Health Care Professionals

 

 

 

Final Scientific Programme

 

Download the programme at this link

 

Faculty

  • Louise Benning (Germany)
  • Marta Jimenez Blanco-Bravo (Spain)
  • Eric Epailly (France)
  • Valentin Goutaudier (France)
  • Delphine Kervella (Spain)
  • Carmen Lefaucheur (France)
  • Guido Moll (Germany)
  • Andriana Nikolova (US)
  • Bianca de Nicolo (Italy)
  • Sook Hyeon Park (US)

 

14 June 2024

Session 1       Introduction of ESOT Guidelines on Biomarkers (14:30 – 16:00)

Moderator: Luciano Potena (Italy)

14:00    Welcome address

Speaker: David Cucchiari (Spain)

14:35    Overview of Biomarkers in Transplantation: What to expect?

Speaker: Carmen Lefaucheur (France)

15:00    Guidelines Presentation: Kidney  ‘European Society of Organ Transplantation Consensus Statement on Testing for Non-Invasive Diagnosis of Kidney Allograft Rejection’

Speaker: Sook Hyeon Park (US)

15:20     Guidelines Presentation: Heart & Lung ‘European Society for Organ Transplantation Statement on the use of non-invasive biomarkers for cardiothoracic transplant rejection surveillance’

Speaker: Andriana Nikolova (US)

 

16:00 – 16:30 Coffee break

 

Session 2       Donor derived cfDNA (16:30 – 18:00)

Moderator: Carmen Lefaucheur (France)

16:30  Challenges of setting up of cfDNA assay

Speaker: Bianca de Nicolo (Italy)

16:55    cfDNA in Kidneys & Pancreas

Speaker: Louise Benning (Germany)

17:20    cfDNA in Heart & Lung

Speaker: Luciano Potena (Italy)

17:45    Panel Discussion

 

15 June 2024

Session 3       Other Biomarkers (09:00 – 10:40)

Moderator: Eric Epailly (France)

09:00    Urinary

Speaker: David Cucchiari (Spain)

09:20    Gene expression

Speaker: Valentin Goutaudier (France)

09:40    Cardiac biomarkers

Speaker: Marta Jimenez Blanco Bravo (Spain)

10:00    Immune function biomarkers

Speaker: Delphine Kervella (Spain)

10:20    HLA and non-HLA donor specific antibodies

Speaker: Guido Moll (Germany)

 

10:40 – 11:00 Coffee break

 

Session 4       Clinical Case Discussion (11:00 – 12:00)

Format: Participants will be divided into two groups. Clinical case studies will be presented and discussed during the session

11:00  Clinical case discussion: Management of subclinical and of relapsing rejection in KTX: how biomarkers could be helpful

Moderators: Louise Benning (Germany), David Cucchiari (Spain)

11:25  Clinical case discussion: Management of rejection treatment in infected patients: how biomarkers can be helpful

Moderators: Marta Jimenez Blanco-Bravo (Spain), Luciano Potena (Italy)

11:50    Closing remarks

Speaker: Luciano Potena (Italy)

 

 

 

Organising Committee
David Cucchiari (Spain), Dilan Dabare (United Kingdom), Luciano Potena (Italy)

Confirmed Speakers

  • Louise Benning (Germany)
  • Marta Jimenez Blanco-Bravo (Spain)
  • David Cucchiari (Spain)
  • Eric Epailly (France)
  • Valentin Goutaudier (France)
  • Delphine Kervella (Spain)
  • Carmen Lefaucheur (France)
  • Guido Moll (Germany)
  • Andriana Nikolova (US)
  • Bianca de Nicolo (Italy)
  • Luciano Potena (Italy)
  • Gianluigi Zaza (Italy)

 

 

Venue

Mercure Hotel Stare Miasto
Pawia 18/B, 31-154 Kraków, Poland

General Information

The official language of the masterclass is English.

This masterclass is open to 25 participants and it is by application only. Registration is provided upon application approval.

Grant application

Successful candidates will receive a 300 EUR grant covering travel expenses. Accommodation will be provided by the Organisers at the venue of the Masterclass. For more information on how to apply, please click here.

Extended Deadline: 10 May 2024 – 23:59 CEST 

Cancellation Policy

Cancellations must be written to Supriya Barve supriya.barve@esot.org

ESOT Membership

Please note that you must be an ESOT member with YPT affiliation in good standing to apply for the Masterclass.
If you have any questions about your affiliation or other inquiries, please do not hesitate to contact the ESOT team  (askme@esot.org).
Check your membership status here

 

Giovanna Rossi – Senior Project Manager
Supriya Barve – Project Coordinator

This masterclass is possible thanks to the kind support of

Masterclass Application

This masterclass is open to 25 participants and it is by application only. Registration is provided upon application approval. Successful candidates will receive a 300 EUR grant covering travel expenses. Accommodation will be provided by the Organisers.

Read the Terms of Reference

Application materials

  1. A letter of motivation including the applicant’s learning objectives in relation to their participation in the masterclass. (max. 1 page)
  2. A brief CV (max. 2 pages).     
  3. A letter signed by the Head of the applicant’s Department in the Home Institution confirming your position.      

NEW Extended Deadline: 10 May 2024 – 23:59 CEST 

  • All documents must be in English.   
  • All applications must be submitted by email to: supriya.barve@esot.org 

Subject: Grant application for ESOT Masterclass 2024 _ Name of the applicant

 

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